Haystack: systematic analysis of the variation of epigenetic states and cell-type specific regulatory elements | Zendy

Luca Pinello | Zendy; Rick Farouni | Zendy; GuoCheng Yuan | Zendy

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Haystack: systematic analysis of the variation of epigenetic states and cell-type specific regulatory elements

Author(s) -

Luca Pinello,

Rick Farouni,

GuoCheng Yuan

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty031

Subject(s) - haystack , epigenetics , variation (astronomy) , computational biology , biology , genetics , computer science , gene , world wide web , physics , astrophysics

With the increasing amount of genomic and epigenomic data in the public domain, a pressing challenge is to integrate these data to investigate the role of epigenetic mechanisms in regulating gene expression and maintenance of cell-identity. To this end, we have implemented a computational pipeline to systematically study epigenetic variability and uncover regulatory DNA sequences.

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