GTC: how to maintain huge genotype collections in a compressed form | Zendy

Agnieszka Danek | Zendy; Sebastian Deorowicz | Zendy

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GTC: how to maintain huge genotype collections in a compressed form

Author(s) -

Agnieszka Danek,

Sebastian Deorowicz

Publication year - 2018

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/bty023

Subject(s) - haplotype , computer science , representation (politics) , database , genotype , information retrieval , data mining , biology , genetics , gene , politics , political science , law

Nowadays, genome sequencing is frequently used in many research centers. In projects, such as the Haplotype Reference Consortium or the Exome Aggregation Consortium, huge databases of genotypes in large populations are determined. Together with the increasing size of these collections, the need for fast and memory frugal ways of representation and searching in them becomes crucial.

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