Multiple hot-deck imputation for network inference from RNA sequencing data
Author(s) -
Alyssa Imbert,
Armand Valsesia,
Caroline Le Gall,
Claudia Armenise,
Grégory Lefebvre,
PierreAntoine Gourraud,
Nathalie Viguerie,
Nathalie VillaVialaneix
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx819
Subject(s) - imputation (statistics) , inference , computer science , data mining , artificial intelligence , machine learning , missing data
Network inference provides a global view of the relations existing between gene expression in a given transcriptomic experiment (often only for a restricted list of chosen genes). However, it is still a challenging problem: even if the cost of sequencing techniques has decreased over the last years, the number of samples in a given experiment is still (very) small compared to the number of genes.
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