MetaCherchant: analyzing genomic context of antibiotic resistance genes in gut microbiota
Author(s) -
Evgenii I. Olekhnovich,
Artem T. Vasilyev,
Vladimir Ulyantsev,
Elena Kostryukova,
Alexander Tyakht
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx681
Subject(s) - metagenomics , mobile genetic elements , biology , resistome , antibiotic resistance , genome , context (archaeology) , computational biology , gene , annotation , genetics , horizontal gene transfer , antibiotics , paleontology
Antibiotic resistance is an important global public health problem. Human gut microbiota is an accumulator of resistance genes potentially providing them to pathogens. It is important to develop tools for identifying the mechanisms of how resistance is transmitted between gut microbial species and pathogens.
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