MATAM: reconstruction of phylogenetic marker genes from short sequencing reads in metagenomes
Author(s) -
Pierre Péricard,
Yoann Dufresne,
Loïc Couderc,
Samuel Blanquart,
Hélène Touzet
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx644
Subject(s) - metagenomics , identification (biology) , computational biology , phylogenetic tree , biology , computer science , dna sequencing , sequence assembly , software , gene , genetics , ecology , gene expression , transcriptome , programming language
Advances in the sequencing of uncultured environmental samples, dubbed metagenomics, raise a growing need for accurate taxonomic assignment. Accurate identification of organisms present within a community is essential to understanding even the most elementary ecosystems. However, current high-throughput sequencing technologies generate short reads which partially cover full-length marker genes and this poses difficult bioinformatic challenges for taxonomy identification at high resolution.
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