LDassoc: an online tool for interactively exploring genome-wide association study results and prioritizing variants for functional investigation | Zendy

Mitchell J. Machiela | Zendy; Stephen J. Chanock | Zendy

Open Access

LDassoc: an online tool for interactively exploring genome-wide association study results and prioritizing variants for functional investigation

Author(s) -

Mitchell J. Machiela,

Stephen J. Chanock

Publication year - 2017

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btx561

Subject(s) - linkage disequilibrium , upload , visualization , genome wide association study , computer science , genetic association , genome browser , plot (graphics) , linkage (software) , association mapping , data mining , genome , genomics , world wide web , biology , genetics , single nucleotide polymorphism , gene , statistics , mathematics , genotype

Existing approaches to plot association results from genome-wide association studies (GWAS) are in the form of static Manhattan plots and often lack data integration with rich databases on variant regulatory potential as well as population-specific linkage disequilibrium patterns.

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