NavMol 3.0: enabling the representation of metabolic reactions by blind users
Author(s) -
Yuri I. Binev,
Daniela Peixoto,
Florbela Pereira,
Ian Rodrigues,
Sofia Cavaco,
Ana M. Lobo,
João AiresdeSousa
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx556
Subject(s) - computer science , cheminformatics , software , visualization , license , representation (politics) , file format , human–computer interaction , world wide web , artificial intelligence , programming language , bioinformatics , operating system , biology , politics , political science , law
The representation of metabolic reactions strongly relies on visualization, which is a major barrier for blind users. The NavMol software renders the communication and interpretation of molecular structures and reactions accessible by integrating chemoinformatics and assistive technology. NavMol 3.0 provides a molecular editor for metabolic reactions. The user can start with templates of reactions and build from such cores. Atom-to-atom mapping enables changes in the reactants to be reflected in the products (and vice-versa) and the reaction centres to be automatically identified. Blind users can easily interact with the software using the keyboard and text-to-speech technology.
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