Open AccessMIRMMR: binary classification of microsatellite instability using methylation and mutations
Author(s) -
Steven M. Foltz,
Wen-Wei Liang,
Mingchao Xie,
Li Ding
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx507
Subject(s) - microsatellite instability , microsatellite , unix , source code , license , genetics , computational biology , biology , computer science , programming language , software , operating system , gene , allele
MIRMMR predicts microsatellite instability status in cancer samples using methylation and mutation information, in contrast to existing methods that rely on observed microsatellites. Additionally, MIRMMR highlights those genetic alterations contributing to microsatellite instability.
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