Open AccessiDNA4mC: identifying DNA N4-methylcytosine sites based on nucleotide chemical properties
Author(s) -
Wei Chen,
Hui Yang,
Pengmian Feng,
Hui Ding,
Hao Lin
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx479
Subject(s) - computer science , web server , dna , genome , computational biology , nucleotide , the internet , biology , genetics , world wide web , gene
DNA N4-methylcytosine (4mC) is an epigenetic modification. The knowledge about the distribution of 4mC is helpful for understanding its biological functions. Although experimental methods have been proposed to detect 4mC sites, they are expensive for performing genome-wide detections. Thus, it is necessary to develop computational methods for predicting 4mC sites.
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