BPP: a sequence-based algorithm for branch point prediction
Author(s) -
Qing Zhang,
Xiaodan Fan,
Yejun Wang,
Ming-an Sun,
Jianlin Shao,
Dianjing Guo
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx401
Subject(s) - sequence (biology) , computer science , algorithm , point (geometry) , mathematics , genetics , geometry , biology
Although high-throughput sequencing methods have been proposed to identify splicing branch points in the human genome, these methods can only detect a small fraction of the branch points subject to the sequencing depth, experimental cost and the expression level of the mRNA. An accurate computational model for branch point prediction is therefore an ongoing objective in human genome research.
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