Flexbar 3.0 – SIMD and multicore parallelization | Zendy

Johannes T. Roehr | Zendy; Christoph Dieterich | Zendy; Knut Reinert | Zendy

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Flexbar 3.0 – SIMD and multicore parallelization

Author(s) -

Johannes T. Roehr,

Christoph Dieterich,

Knut Reinert

Publication year - 2017

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btx330

Subject(s) - computer science , simd , parallel computing , adapter (computing) , barcode , preprocessor , multi core processor , dna sequencing , artificial intelligence , computer hardware , biology , operating system , dna , genetics

High-throughput sequencing machines can process many samples in a single run. For Illumina systems, sequencing reads are barcoded with an additional DNA tag that is contained in the respective sequencing adapters. The recognition of barcode and adapter sequences is hence commonly needed for the analysis of next-generation sequencing data. Flexbar performs demultiplexing based on barcodes and adapter trimming for such data. The massive amounts of data generated on modern sequencing machines demand that this preprocessing is done as efficiently as possible.

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