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The RNASeq-er API—a gateway to systematically updated analysis of public RNA-seq data
Author(s) -
Robert Petryszak,
Nuno A. Fonseca,
Anja Füllgrabe,
Laura Huerta,
Maria Keays,
Amy Tang,
Alvis Brāzma
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx143
Subject(s) - computer science , rna seq , raw data , application programming interface , gateway (web page) , exon , computational biology , rna , web service , database , world wide web , information retrieval , biology , gene , transcriptome , gene expression , genetics , programming language
The exponential growth of publicly available RNA-sequencing (RNA-Seq) data poses an increasing challenge to researchers wishing to discover, analyse and store such data, particularly those based in institutions with limited computational resources. EMBL-EBI is in an ideal position to address these challenges and to allow the scientific community easy access to not just raw, but also processed RNA-Seq data. We present a Web service to access the results of a systematically and continually updated standardized alignment as well as gene and exon expression quantification of all public bulk (and in the near future also single-cell) RNA-Seq runs in 264 species in European Nucleotide Archive, using Representational State Transfer.

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