Fast, clash-free RNA conformational morphing using molecular junctions | Zendy

Amélie Héliou | Zendy; Dominik Budday | Zendy; Rasmus Fonseca | Zendy; Henry van den Bedem | Zendy

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Fast, clash-free RNA conformational morphing using molecular junctions

Author(s) -

Amélie Héliou,

Dominik Budday,

Rasmus Fonseca,

Henry van den Bedem

Publication year - 2017

Publication title -

bioinformatics

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btx127

Subject(s) - morphing , rna , computer science , biophysics , computational biology , chemistry , computer graphics (images) , biology , biochemistry , gene

Non-coding ribonucleic acids (ncRNA) are functional RNA molecules that are not translated into protein. They are extremely dynamic, adopting diverse conformational substates, which enables them to modulate their interaction with a large number of other molecules. The flexibility of ncRNA provides a challenge for probing their complex 3D conformational landscape, both experimentally and computationally.

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