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Extracting morphologies from third harmonic generation images of structurally normal human brain tissue
Author(s) -
Andy Zhang,
Nikolay V. Kuzmin,
Marie Louise Groot,
Jan C. de Munck
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx035
Subject(s) - computer science , correctness , segmentation , artificial intelligence , pattern recognition (psychology) , neuropil , benchmark (surveying) , computer vision , image (mathematics) , image segmentation , human brain , software , algorithm , biology , neuroscience , programming language , geography , central nervous system , geodesy
The morphologies contained in 3D third harmonic generation (THG) images of human brain tissue can report on the pathological state of the tissue. However, the complexity of THG brain images makes the usage of modern image processing tools, especially those of image filtering, segmentation and validation, to extract this information challenging.

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