Open AccesschainCleaner improves genome alignment specificity and sensitivity
Author(s) -
Hernando G. Suárez Duran,
Björn E. Langer,
Pradnya Ladde,
Michael Hiller
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btx024
Subject(s) - genome , pseudogene , comparative genomics , computational biology , genomics , biology , human genome , genetics , gene , computer science
Accurate alignments between entire genomes are crucial for comparative genomics. However, computing sensitive and accurate genome alignments is a challenging problem, complicated by genomic rearrangements.
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