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CircosVCF: circos visualization of whole-genome sequence variations stored in VCF files
Author(s) -
Elyashiv Drori,
Dan Levy,
Pola SmirinYosef,
Oshrit Rahimi,
Mali SalmonDivon
Publication year - 2017
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw834
Subject(s) - visualization , genome browser , computer science , javascript , context (archaeology) , plot (graphics) , software , genome , data visualization , interactive visualization , web application , identification (biology) , world wide web , data mining , genomics , biology , programming language , genetics , paleontology , statistics , mathematics , botany , gene
Visualization of whole-genomic variations in a meaningful manner assists researchers in gaining new insights into the underlying data, especially when it comes in the context of whole genome comparisons. CircosVCF is a web based visualization tool for genome-wide variant data described in VCF files, using circos plots. The user friendly interface of CircosVCF supports an interactive design of the circles in the plot, and the integration of additional information such as experimental data or annotations. The provided visualization capabilities give a broad overview of the genomic relationships between genomes, and allow identification of specific meaningful SNPs regions.

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