RENT+: an improved method for inferring local genealogical trees from haplotypes with recombination | Zendy

Sajad Mirzaei | Zendy; Yufeng Wu | Zendy

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RENT+: an improved method for inferring local genealogical trees from haplotypes with recombination

Author(s) -

Sajad Mirzaei,

Yufeng Wu

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw735

Subject(s) - haplotype , recombination , biology , genetics , evolutionary biology , computational biology , computer science , genealogy , gene , genotype , history

: Haplotypes from one or multiple related populations share a common genealogical history. If this shared genealogy can be inferred from haplotypes, it can be very useful for many population genetics problems. However, with the presence of recombination, the genealogical history of haplotypes is complex and cannot be represented by a single genealogical tree. Therefore, inference of genealogical history with recombination is much more challenging than the case of no recombination.

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