iSmaRT: a toolkit for a comprehensive analysis of small RNA-Seq data | Zendy

Riccardo Panero | Zendy; Antonio Rinaldi | Zendy; Domenico Memoli | Zendy; Giovanni Nassa | Zendy; Maria Ravo | Zendy; Francesca Rizzo | Zendy; Roberta Tarallo | Zendy; Luciano Milanesi | Zendy; Alessandro Weisz | Zendy; Giorgio Giurato | Zendy

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iSmaRT: a toolkit for a comprehensive analysis of small RNA-Seq data

Author(s) -

Riccardo Panero,

Antonio Rinaldi,

Domenico Memoli,

Giovanni Nassa,

Maria Ravo,

Francesca Rizzo,

Roberta Tarallo,

Luciano Milanesi,

Alessandro Weisz,

Giorgio Giurato

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw734

Subject(s) - computer science , pipeline (software) , graphical user interface , password , data mining , computational biology , biology , programming language , operating system

The interest in investigating the biological roles of small non-coding RNAs (sncRNAs) is increasing, due to the pleiotropic effects of these molecules exert in many biological contexts. While several methods and tools are available to study microRNAs (miRNAs), only few focus on novel classes of sncRNAs, in particular PIWI-interacting RNAs (piRNAs). To overcome these limitations, we implemented iSmaRT ( i ntegrative Sm all R NA T ool-kit), an automated pipeline to analyze smallRNA-Seq data.

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