Expanding the toolkit for membrane protein modeling in Rosetta | Zendy

Julia Koehler Leman | Zendy; Benjamin K. Mueller | Zendy; Jeffrey J. Gray | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Expanding the toolkit for membrane protein modeling in Rosetta

Author(s) -

Julia Koehler Leman,

Benjamin K. Mueller,

Jeffrey J. Gray

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw716

Subject(s) - suite , computer science , flexibility (engineering) , software , embedding , software suite , set (abstract data type) , membrane protein , software engineering , computational biology , artificial intelligence , programming language , membrane , chemistry , biology , statistics , mathematics , archaeology , history , biochemistry

A range of membrane protein modeling tools has been developed in the past 5-10 years, yet few of these tools are integrated and make use of existing functionality for soluble proteins. To extend existing methods in the Rosetta biomolecular modeling suite for membrane proteins, we recently implemented RosettaMP, a general framework for membrane protein modeling. While RosettaMP facilitates implementation of new methods, addressing real-world biological problems also requires a set of accessory tools that are used to carry out standard modeling tasks.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research