QAcon: single model quality assessment using protein structural and contact information with machine learning techniques
Author(s) -
Renzhi Cao,
Badri Adhikari,
Debswapna Bhattacharya,
Miao Sun,
Jie Hou,
Jianlin Cheng
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw694
Subject(s) - computer science , source code , data mining , machine learning , artificial intelligence , protein structure prediction , artificial neural network , quality assessment , quality (philosophy) , feature (linguistics) , software , evaluation methods , protein structure , reliability engineering , philosophy , linguistics , physics , epistemology , nuclear magnetic resonance , engineering , programming language , operating system
Protein model quality assessment (QA) plays a very important role in protein structure prediction. It can be divided into two groups of methods: single model and consensus QA method. The consensus QA methods may fail when there is a large portion of low quality models in the model pool.
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