GeneEvolve: a fast and memory efficient forward-time simulator of realistic whole-genome sequence and SNP data
Author(s) -
Rasool Tahmasbi,
Matthew C. Keller
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw606
Subject(s) - computer science , sequence (biology) , snp , whole genome sequencing , computational biology , genome , genetics , biology , single nucleotide polymorphism , genotype , gene
Computer simulations are excellent tools for understanding the evolutionary and genetic consequences of complex processes that cannot be analytically predicted and for creating realistic genetic data. There are many software packages that simulate genetic data, but they are typically not fast or memory efficient enough to simulate realistic, individual-level genome-wide SNP/sequence data.
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