iRSpot-EL: identify recombination spots with an ensemble learning approach
Author(s) -
Bin Liu,
Shanyi Wang,
Long Ren,
KuoChen Chou
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw539
Subject(s) - computer science , genome , cluster analysis , benchmark (surveying) , recombination , homologous recombination , genome browser , data mining , genomics , computational biology , machine learning , biology , genetics , dna , gene , geodesy , geography
Coexisting in a DNA system, meiosis and recombination are two indispensible aspects for cell reproduction and growth. With the avalanche of genome sequences emerging in the post-genomic age, it is an urgent challenge to acquire the information of DNA recombination spots because it can timely provide very useful insights into the mechanism of meiotic recombination and the process of genome evolution.
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