DOMINO: development of informative molecular markers for phylogenetic and genome-wide population genetic studies in non-model organisms | Zendy

Cristina Frías-López | Zendy; Jose Francisco SánchezHerrero | Zendy; Sara GuiraoRico | Zendy; Elisa Mora | Zendy; Miquel A. Arnedo | Zendy; Alejandro SánchezGracia | Zendy; Julio Rozas | Zendy

Open Access

DOMINO: development of informative molecular markers for phylogenetic and genome-wide population genetic studies in non-model organisms

Author(s) -

Cristina Frías-López,

Jose Francisco SánchezHerrero,

Sara GuiraoRico,

Elisa Mora,

Miquel A. Arnedo,

Alejandro SánchezGracia,

Julio Rozas

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw534

Subject(s) - computational biology , genotyping , biology , population , phylogenetic tree , computer science , dna sequencing , genetics , gene , demography , sociology , genotype

The development of molecular markers is one of the most important challenges in phylogenetic and genome wide population genetics studies, especially in studies with non-model organisms. A highly promising approach for obtaining suitable markers is the utilization of genomic partitioning strategies for the simultaneous discovery and genotyping of a large number of markers. Unfortunately, not all markers obtained from these strategies provide enough information for solving multiple evolutionary questions at a reasonable taxonomic resolution.

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