Estimating and testing high-dimensional mediation effects in epigenetic studies | Zendy

Haixiang Zhang | Zendy; Yinan Zheng | Zendy; Zhou Zhang | Zendy; Tao Gao | Zendy; Brian T. Joyce | Zendy; Grace Yoon | Zendy; Wei Zhang | Zendy; Joel Schwartz | Zendy; Allan C. Just | Zendy; Elena Colicino | Zendy; Pantel Vokonas | Zendy; Lihui Zhao | Zendy; Jinchi Lv | Zendy; Andrea Baccarelli | Zendy; Lifang Hou | Zendy; Lei Liu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Estimating and testing high-dimensional mediation effects in epigenetic studies

Author(s) -

Haixiang Zhang,

Yinan Zheng,

Zhou Zhang,

Tao Gao,

Brian T. Joyce,

Grace Yoon,

Wei Zhang,

Joel Schwartz,

Allan C. Just,

Elena Colicino,

Pantel Vokonas,

Lihui Zhao,

Jinchi Lv,

Andrea Baccarelli,

Lifang Hou,

Lei Liu

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw351

Subject(s) - epigenetics , mediation , computer science , computational biology , econometrics , biology , psychology , genetics , statistics , mathematics , gene , sociology , social science

High-dimensional DNA methylation markers may mediate pathways linking environmental exposures with health outcomes. However, there is a lack of analytical methods to identify significant mediators for high-dimensional mediation analysis.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research