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Top-down analysis of protein samples by de novo sequencing techniques
Author(s) -
Kira Vyatkina,
Si Wu,
Lennard J. M. Dekker,
Martijn M. VanDuijn,
Xiaowen Liu,
Nikola Tolić,
Theo M. Luider,
Ljiljana PašaTolić,
Pavel A. Pevzner
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw307
Subject(s) - computer science , computational biology , mass spectrometry , tandem mass spectrometry , protein sequencing , sequence analysis , protein methods , algorithm , peptide sequence , biology , chemistry , genetics , chromatography , dna , gene
Recent technological advances have made high-resolution mass spectrometers affordable to many laboratories, thus boosting rapid development of top-down mass spectrometry, and implying a need in efficient methods for analyzing this kind of data.

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