Evaluation of hybrid and non-hybrid methods for de novo assembly of nanopore reads
Author(s) -
Ivan Sović,
Krešimir Križanović,
Karolj Skala,
Mile Šikić
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw237
Subject(s) - minion , nanopore sequencing , nanopore , sequence assembly , computer science , benchmark (surveying) , benchmarking , contig , hybrid genome assembly , genome , dna sequencing , computational biology , data mining , biology , nanotechnology , gene , genetics , materials science , gene expression , transcriptome , geodesy , marketing , geography , business
Recent emergence of nanopore sequencing technology set a challenge for established assembly methods. In this work, we assessed how existing hybrid and non-hybrid de novo assembly methods perform on long and error prone nanopore reads.
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