CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets | Zendy

Ellen Schofield | Zendy; T.L.W. Carver | Zendy; Premanand Achuthan | Zendy; Paula Freire-Pritchett | Zendy; Mikhail Spivakov | Zendy; John A. Todd | Zendy; Oliver S. Burren | Zendy

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CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets

Author(s) -

Ellen Schofield,

T.L.W. Carver,

Premanand Achuthan,

Paula Freire-Pritchett,

Mikhail Spivakov,

John A. Todd,

Oliver S. Burren

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw173

Subject(s) - visualization , html5 , computer science , genome browser , interactive visualization , source code , world wide web , web application , genome , genomics , biology , data mining , gene , programming language , genetics

Promoter capture Hi-C (PCHi-C) allows the genome-wide interrogation of physical interactions between distal DNA regulatory elements and gene promoters in multiple tissue contexts. Visual integration of the resultant chromosome interaction maps with other sources of genomic annotations can provide insight into underlying regulatory mechanisms. We have developed Capture HiC Plotter (CHiCP), a web-based tool that allows interactive exploration of PCHi-C interaction maps and integration with both public and user-defined genomic datasets.

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