Coala: an R framework for coalescent simulation | Zendy

Paul Staab | Zendy; Dirk Metzler | Zendy

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Coala: an R framework for coalescent simulation

Author(s) -

Paul Staab,

Dirk Metzler

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw098

Subject(s) - coalescent theory , computer science , license , r package , syntax , theoretical computer science , algorithm , programming language , artificial intelligence , biology , phylogenetic tree , biochemistry , gene , operating system

Simulation programs based on the coalescent efficiently generate genetic data according to a given model of evolution. We present coala, an R package for calling coalescent simulators with a unified syntax. It can execute simulations with several programs, calculate additional summary statistics and combine multiple simulations to create biologically more realistic data.

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