Open AccessPON-Sol: prediction of effects of amino acid substitutions on protein solubility
Author(s) -
Yang Yang,
Abhishek Niroula,
Bairong Shen,
Mauno Vihinen
Publication year - 2016
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btw066
Subject(s) - solubility , chemistry , test set , amino acid , computer science , biochemistry , artificial intelligence , organic chemistry
Solubility is one of the fundamental protein properties. It is of great interest because of its relevance to protein expression. Reduced solubility and protein aggregation are also associated with many diseases.
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