TFBSTools: an R/bioconductor package for transcription factor binding site analysis | Zendy

Ge Tan | Zendy; Boris Lenhard | Zendy

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TFBSTools: an R/bioconductor package for transcription factor binding site analysis

Author(s) -

Ge Tan,

Boris Lenhard

Publication year - 2016

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btw024

Subject(s) - bioconductor , r package , dna binding site , computer science , visualization , data mining , transcription factor , software , computational biology , mit license , biology , gene , genetics , operating system , programming language , gene expression , promoter

: The ability to efficiently investigate transcription factor binding sites (TFBSs) genome-wide is central to computational studies of gene regulation. TFBSTools is an R/Bioconductor package for the analysis and manipulation of TFBSs and their associated transcription factor profile matrices. TFBStools provides a toolkit for handling TFBS profile matrices, scanning sequences and alignments including whole genomes, and querying the JASPAR database. The functionality of the package can be easily extended to include advanced statistical analysis, data visualization and data integration.

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