OfftargetFinder: a web tool for species-specific RNAi design | Zendy

Robert T. Good | Zendy; Tincy Varghese | Zendy; John F. Golz | Zendy; D.A. Russell | Zendy; Alexie Papanicolaou | Zendy; Owain R. Edwards | Zendy; Charles Robin | Zendy

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OfftargetFinder: a web tool for species-specific RNAi design

Author(s) -

Robert T. Good,

Tincy Varghese,

John F. Golz,

D.A. Russell,

Alexie Papanicolaou,

Owain R. Edwards,

Charles Robin

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv747

Subject(s) - rna interference , biology , computational biology , computer science , interference (communication) , genetics , rna , gene , telecommunications , channel (broadcasting)

RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process.

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