Extending gene ontology with gene association networks | Zendy

Jiajie Peng | Zendy; Tao Wang | Zendy; Jixuan Wang | Zendy; Yadong Wang | Zendy; Jin Chen | Zendy

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Extending gene ontology with gene association networks

Author(s) -

Jiajie Peng,

Tao Wang,

Jixuan Wang,

Yadong Wang,

Jin Chen

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv712

Subject(s) - computer science , construct (python library) , gene ontology , biological network , ontology , component (thermodynamics) , process (computing) , software , biological database , association (psychology) , gene regulatory network , data mining , resource (disambiguation) , gene nomenclature , artificial intelligence , gene , computational biology , bioinformatics , programming language , biology , taxonomy (biology) , computer network , biochemistry , gene expression , philosophy , physics , epistemology , thermodynamics , botany , nomenclature

Gene ontology (GO) is a widely used resource to describe the attributes for gene products. However, automatic GO maintenance remains to be difficult because of the complex logical reasoning and the need of biological knowledge that are not explicitly represented in the GO. The existing studies either construct whole GO based on network data or only infer the relations between existing GO terms. None is purposed to add new terms automatically to the existing GO.

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