Evaluation of hierarchical models for integrative genomic analyses
Author(s) -
Marie Denis,
Mahlet G. Tadesse
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv653
Subject(s) - computer science , source code , biological data , data type , data mining , computational biology , bioinformatics , biology , programming language , operating system
Advances in high-throughput technologies have led to the acquisition of various types of -omic data on the same biological samples. Each data type gives independent and complementary information that can explain the biological mechanisms of interest. While several studies performing independent analyses of each dataset have led to significant results, a better understanding of complex biological mechanisms requires an integrative analysis of different sources of data.
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