MMR: a tool for read multi-mapper resolution | Zendy

André Kahles | Zendy; Jonas Behr | Zendy; Gunnar Rätsch | Zendy

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MMR: a tool for read multi-mapper resolution

Author(s) -

André Kahles,

Jonas Behr,

Gunnar Rätsch

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv624

Subject(s) - computer science , data mining , source code , documentation , software , computational biology , programming language , biology

Mapping high-throughput sequencing data to a reference genome is an essential step for most analysis pipelines aiming at the computational analysis of genome and transcriptome sequencing data. Breaking ties between equally well mapping locations poses a severe problem not only during the alignment phase but also has significant impact on the results of downstream analyses. We present the multi-mapper resolution (MMR) tool that infers optimal mapping locations from the coverage density of other mapped reads.

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