Open AccesscaRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens
Author(s) -
Jan Winter,
Marco Breinig,
Florian Heigwer,
Dirk Brügemann,
Svenja Leible,
Oliver Pelz,
Tianzuo Zhan,
Michael Boutros
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv617
Subject(s) - crispr , workflow , computer science , documentation , software , cas9 , computational biology , operating system , database , biology , genetics , gene
Genetic screens by CRISPR/Cas9-mediated genome engineering have become a powerful tool for functional genomics. However, there is currently a lack of end-to-end software pipelines to analyze CRISPR/Cas9 screens based on next generation sequencing.
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