Approximately independent linkage disequilibrium blocks in human populations
Author(s) -
Tomaz Berisa,
Joseph K. Pickrell
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv546
Subject(s) - linkage disequilibrium , disequilibrium , linkage (software) , computer science , human genome , genome , genetic association , computational biology , biology , genetics , gene , haplotype , single nucleotide polymorphism , allele , genotype , medicine , ophthalmology
We present a method to identify approximately independent blocks of linkage disequilibrium in the human genome. These blocks enable automated analysis of multiple genome-wide association studies.
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