RASER: reads aligner for SNPs and editing sites of RNA | Zendy

Jaegyoon Ahn | Zendy; Xinshu Xiao | Zendy

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RASER: reads aligner for SNPs and editing sites of RNA

Author(s) -

Jaegyoon Ahn,

Xinshu Xiao

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv505

Subject(s) - computer science , identification (biology) , computational biology , snp , single nucleotide polymorphism , rna , tree (set theory) , data mining , genetics , biology , gene , genotype , mathematics , mathematical analysis , botany

Accurate identification of genetic variants such as single-nucleotide polymorphisms (SNPs) or RNA editing sites from RNA-Seq reads is important, yet challenging, because it necessitates a very low false-positive rate in read mapping. Although many read aligners are available, no single aligner was specifically developed or tested as an effective tool for SNP and RNA editing prediction.

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