Open AccessTIPR: transcription initiation pattern recognition on a genome scale
Author(s) -
Taj Morton,
WengKeen Wong,
Molly Megraw
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv464
Subject(s) - genome , computer science , computational biology , gene , biology , transcription (linguistics) , identification (biology) , chromosome , genetics , linguistics , philosophy , botany
The computational identification of gene transcription start sites (TSSs) can provide insights into the regulation and function of genes without performing expensive experiments, particularly in organisms with incomplete annotations. High-resolution general-purpose TSS prediction remains a challenging problem, with little recent progress on the identification and differentiation of TSSs which are arranged in different spatial patterns along the chromosome.
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