Identifying novel associations between small molecules and miRNAs based on integrated molecular networks | Zendy

Yingli Lv | Zendy; Shuyuan Wang | Zendy; Fanlin Meng | Zendy; Lei Yang | Zendy; Zhifeng Wang | Zendy; Jing Wang | Zendy; Xiaowen Chen | Zendy; Wei Jiang | Zendy; Yixue Li | Zendy; Xia Li | Zendy

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Identifying novel associations between small molecules and miRNAs based on integrated molecular networks

Author(s) -

Yingli Lv,

Shuyuan Wang,

Fanlin Meng,

Lei Yang,

Zhifeng Wang,

Jing Wang,

Xiaowen Chen,

Wei Jiang,

Yixue Li,

Xia Li

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv417

Subject(s) - microrna , identification (biology) , computational biology , small molecule , biology , computer science , bioinformatics , gene , genetics , botany

miRNAs play crucial roles in human diseases and newly discovered could be targeted by small molecule (SM) drug compounds. Thus, the identification of small molecule drug compounds (SM) that target dysregulated miRNAs in cancers will provide new insight into cancer biology and accelerate drug discovery for cancer therapy.

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