Open AccessError filtering, pair assembly and error correction for next-generation sequencing reads
Author(s) -
R. C. Edgar,
Henrik Flyvbjerg
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv401
Subject(s) - computer science , word error rate , error detection and correction , sequence (biology) , algorithm , amplicon sequencing , sequence assembly , amplicon , dna sequencing , artificial intelligence , biology , genetics , dna , polymerase chain reaction , 16s ribosomal rna , bacteria , gene , gene expression , transcriptome
Next-generation sequencing produces vast amounts of data with errors that are difficult to distinguish from true biological variation when coverage is low.
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