LFQC: a lossless compression algorithm for FASTQ files | Zendy

Marius Nicolae | Zendy; Sudipta Pathak | Zendy; Sanguthevar Rajasekaran | Zendy

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LFQC: a lossless compression algorithm for FASTQ files

Author(s) -

Marius Nicolae,

Sudipta Pathak,

Sanguthevar Rajasekaran

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv384

Subject(s) - lossless compression , computer science , data compression , redundancy (engineering) , algorithm , data mining , implementation , lossy compression , operating system , software engineering

Next Generation Sequencing (NGS) technologies have revolutionized genomic research by reducing the cost of whole genome sequencing. One of the biggest challenges posed by modern sequencing technology is economic storage of NGS data. Storing raw data is infeasible because of its enormous size and high redundancy. In this article, we address the problem of storage and transmission of large FASTQ files using innovative compression techniques.

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