Forna (force-directed RNA): Simple and effective online RNA secondary structure diagrams | Zendy

Peter Kerpedjiev | Zendy; Stefan Hammer | Zendy; Ivo L. Hofacker | Zendy

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Forna (force-directed RNA): Simple and effective online RNA secondary structure diagrams

Author(s) -

Peter Kerpedjiev,

Stefan Hammer,

Ivo L. Hofacker

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv372

Subject(s) - computer science , visualization , nucleic acid secondary structure , software , source code , simple (philosophy) , interactivity , protein secondary structure , interface (matter) , data structure , world wide web , rna , information retrieval , programming language , data mining , biology , biochemistry , philosophy , epistemology , bubble , maximum bubble pressure method , parallel computing , gene

The secondary structure of RNA is integral to the variety of functions it carries out in the cell and its depiction allows researchers to develop hypotheses about which nucleotides and base pairs are functionally relevant. Current approaches to visualizing secondary structure provide an adequate platform for the conversion of static text-based representations to 2D images, but are limited in their offer of interactivity as well as their ability to display larger structures, multiple structures and pseudoknotted structures.

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