Open Accesstmle.npvi: targeted, integrative search of associations between DNA copy number and gene expression, accounting for DNA methylation
Author(s) -
Antoine Chambaz,
Pierre Neuvial
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv320
Subject(s) - dna methylation , computational biology , dna , gene , biology , genetics , copy number variation , dna sequencing , genome , gene expression
We describe the implementation of the method introduced by Chambaz et al. in 2012. We also demonstrate its genome-wide application to the integrative search of new regions with strong association between DNA copy number and gene expression accounting for DNA methylation in breast cancers.
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