A novel essential domain perspective for exploring gene essentiality | Zendy

Yao Lu | Zendy; Yulan Lu | Zendy; Jingyuan Deng | Zendy; Hai Peng | Zendy; Hui Lü | Zendy; Long Lu | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

A novel essential domain perspective for exploring gene essentiality

Author(s) -

Yao Lu,

Yulan Lu,

Jingyuan Deng,

Hai Peng,

Hui Lü,

Long Lu

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv312

Subject(s) - gene , computational biology , biology , gene prediction , perspective (graphical) , domain (mathematical analysis) , annotation , protein domain , genetics , computer science , genome , artificial intelligence , mathematical analysis , mathematics

Genes with indispensable functions are identified as essential; however, the traditional gene-level studies of essentiality have several limitations. In this study, we characterized gene essentiality from a new perspective of protein domains, the independent structural or functional units of a polypeptide chain.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research