The SwissLipids knowledgebase for lipid biology
Author(s) -
Lucila Aimo,
Robin Liechti,
Nevila HykaNouspikel,
Anne Niknejad,
Anne Gleizes,
Lou Götz,
Dmitry Kuznetsov,
Fabrice David,
Gijs R. van den Brink,
Howard Riezman,
Lydie Bougueleret,
Ioannis Xénarios,
Alan Bridge
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv285
Subject(s) - computational biology , computer science , biomedicine , lipidomics , systems biology , hierarchy , resource (disambiguation) , lipid metabolism , in silico , data science , biology , bioinformatics , biochemistry , computer network , economics , gene , market economy
Lipids are a large and diverse group of biological molecules with roles in membrane formation, energy storage and signaling. Cellular lipidomes may contain tens of thousands of structures, a staggering degree of complexity whose significance is not yet fully understood. High-throughput mass spectrometry-based platforms provide a means to study this complexity, but the interpretation of lipidomic data and its integration with prior knowledge of lipid biology suffers from a lack of appropriate tools to manage the data and extract knowledge from it.
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