Inferring data-specific micro-RNA function through the joint ranking of micro-RNA and pathways from matched micro-RNA and gene expression data | Zendy

Ellis Patrick | Zendy; Michael Buckley | Zendy; Samuel Müller | Zendy; David Lin | Zendy; Jean Yang | Zendy

Open Access

Inferring data-specific micro-RNA function through the joint ranking of micro-RNA and pathways from matched micro-RNA and gene expression data

Author(s) -

Ellis Patrick,

Michael Buckley,

Samuel Müller,

David Lin,

Jean Yang

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv220

Subject(s) - rna , leverage (statistics) , annotation , computational biology , computer science , ranking (information retrieval) , function (biology) , artificial intelligence , gene , biology , genetics

In practice, identifying and interpreting the functional impacts of the regulatory relationships between micro-RNA and messenger-RNA is non-trivial. The sheer scale of possible micro-RNA and messenger-RNA interactions can make the interpretation of results difficult.

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