Two-group comparisons of zero-inflated intensity values: the choice of test statistic matters | Zendy

Andreas Gleiß | Zendy; Mohammed Dakna | Zendy; Harald Mischak | Zendy; Georg Heinze | Zendy

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Two-group comparisons of zero-inflated intensity values: the choice of test statistic matters

Author(s) -

Andreas Gleiß,

Mohammed Dakna,

Harald Mischak,

Georg Heinze

Publication year - 2015

Publication title -

bioinformatics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.599

H-Index - 390

eISSN - 1367-4811

pISSN - 1367-4803

DOI - 10.1093/bioinformatics/btv154

Subject(s) - statistic , statistics , zero (linguistics) , test statistic , intensity (physics) , group (periodic table) , test (biology) , mathematics , econometrics , computer science , statistical hypothesis testing , physics , biology , optics , philosophy , linguistics , paleontology , quantum mechanics

A special characteristic of data from molecular biology is the frequent occurrence of zero intensity values which can arise either by true absence of a compound or by a signal that is below a technical limit of detection.

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