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Acquire: an open-source comprehensive cancer biobanking system
Author(s) -
Heidi Dowst,
Benjamin Pew,
Chris Watkins,
Apollo McOwiti,
Jonathan Barney,
Shijing Qu,
Lauren B. Becnel
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btv012
Subject(s) - biobank , workflow , computer science , suite , resource (disambiguation) , quality (philosophy) , open source , world wide web , bioinformatics , database , biology , software , operating system , history , computer network , philosophy , archaeology , epistemology
The probability of effective treatment of cancer with a targeted therapeutic can be improved for patients with defined genotypes containing actionable mutations. To this end, many human cancer biobanks are integrating more tightly with genomic sequencing facilities and with those creating and maintaining patient-derived xenografts (PDX) and cell lines to provide renewable resources for translational research.

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