Co-expression analysis of high-throughput transcriptome sequencing data with Poisson mixture models
Author(s) -
Andréa Rau,
Cathy Maugis-Rabusseau,
Marie-Laure Martin-Magniette,
Gilles Celeux
Publication year - 2015
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu845
Subject(s) - cluster analysis , computer science , normalization (sociology) , poisson distribution , data mining , context (archaeology) , computational biology , rna seq , data set , set (abstract data type) , transcriptome , gene , gene expression , biology , machine learning , artificial intelligence , statistics , genetics , mathematics , paleontology , sociology , anthropology , programming language
In recent years, gene expression studies have increasingly made use of high-throughput sequencing technology. In turn, research concerning the appropriate statistical methods for the analysis of digital gene expression (DGE) has flourished, primarily in the context of normalization and differential analysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom