GenePainter v. 2.0 resolves the taxonomic distribution of intron positions
Author(s) -
Stefanie Mühlhausen,
Marcel Hellkamp,
Martin Kollmar
Publication year - 2014
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btu798
Subject(s) - intron , distribution (mathematics) , computational biology , biology , computer science , evolutionary biology , genetics , mathematics , gene , mathematical analysis
Conserved intron positions in eukaryotic genes can be used to reconstruct phylogenetic trees, to resolve ambiguous subfamily relationships in protein families and to infer the history of gene families. This version of GenePainter facilitates working with large datasets through options to select specific subsets for analysis and visualization, and through providing exhaustive statistics. GenePainter's application in phylogenetic analyses is considerably extended by the newly implemented integration of the exon-intron pattern conservation with phylogenetic trees.
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